Although sociologists have explored how political and economic factors influence the formation of ignorance in science and technology, we know little about how scientists comply with external controls by abandoning their prior research and leaving scientific innovations incomplete. Most research in science and technology studies (STS) on ignorance has relied on structural and historical analyses, lacking in situ studies in scientific laboratories. Drawing on ethnographic research, this article examines the habitus of ignorance as a mechanism of the social production of ignorance. Scientists have a set of dispositions that establish practical contexts enabling them to ignore particular scientific content. Leaders of the organization repeatedly legitimate the abandonment of unfinished projects, while ordinary laboratory scientists internalize the normalized view that the scientific field is inherently opportunistic and that unfunded research should be left undone. A cycle of legitimation and acceptance of ignorance by actors at distinctive positions within the organization provides a mechanism of social control of scientific knowledge. As the mechanism is habitually self-governed by the rules of the game of current scientific institutions, the result is an indirect, although deeply subjugating, invisible and consolidating form of political and economic domination of the scientific field. © The Author(s) 2019.